Leonard, Sheldon and Howard try to advance the cause of women in science by speaking with junior high girls about their future careers, while Raj plans his date with Lucy.
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To open or not to open? When Howard finds a letter from his father, he's forced to confront his past. And Leonard and Penny throw a grown-up cocktail party at the apartment.
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After one of his favorite TV shows gets canceled too soon, Sheldon feels lost, so Amy tries to help him get over his compulsive need for closure by retraining his brain.
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Leonard and Sheldon hire Professor Proton (guest star BOB NEWHART), the host of their favorite childhood TV show to perform. Raj leaves his dog with Howard and Bernadette.
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When the girls' trip to Vegas falls through, the guys invite them to a Dungeons & Dragons date night that causes Sheldon and Amy's relationship to take an unexpected turn.
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Leonard is away at sea, so Sheldon & Penny spend some time together and spill some revealing secrets. Meanwhile, Howard comes to Raj's aid after his breakup with his girlfriend.
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Leonard returns from the North Sea expedition and finds things chilly between him and Sheldon, while Howard's relationship with his mother opens the door to questions about his masculinity.
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Sheldon is fit to be tied when Amy ruins one of his favorite adventure films, while Leonard finds the key to getting Penny to do his bidding, and Raj & Stuart get creative with their online-dating profiles.
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Sheldon makes a major scientific breakthrough, but he feels it may haunt him for the rest of career. Meanwhile, Howard makes a grand romantic gesture to Bernadette, which causes Penny to put more effort into her relationship with Leonard.
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When Sheldon's childhood hero, Professor Proton, seeks Leonard's help with an experiment, the slighted Sheldon goes nuclear and decides to get revenge by befriending another TV science guy.
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Leonard fails to stop Sheldon from overreacting after a past slight comes to light, and as punishment Leonard must walk a mile in Sheldon's shoes. Meanwhile, Penny has a run-in with Raj's former girlfriend Lucy.
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When Sheldon's accidental scientific discovery is disproved, Amy and Leonard try to help him deal with the shame and the disappointment. Meanwhile, Howard and Bernadette open their home to Raj for a week.
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With Sheldon in Texas, the gang gathers to decorate for Christmas, and they contemplate if each would have had a wonderful life had they never met him.
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Penny turns to Leonard for comfort after her guest appearance on NCIS does not turn out well. She ends up putting Leonard on the spot regarding their relationship. Sheldon works on his sense of humor and Raj practices talking to girls.
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There's impactful news on the work front as Penny makes a big step toward pursuing a full-time acting career, and Sheldon is forced to take a vacation.
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