Stan takes Francine on a surprise trip to Sacramento, but Francine is bored. They meet the Naughty Stewardesses, four women who use their status as flight attendants to find love and adventure.
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Stan thinks that Steve and his friends spend too much time indoors playing video games. He wishes that the boys would go outside and have the kind of adventures in the woods that he had as a child.
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Francine is frustrated that Stan only pretends to pay attention when she talks. Stan takes a pill engineered by the C.I.A. to help male agents listen to females. Stan takes too much and the pill physically transforms him into a woman.
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Stan is tired of Hayley being lazy and unemployed, so he forces her to take a job in Roger's bar. Deputy Director Bullock is a regular at the bar, and he confesses his secrets to Hayley.
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Stan is fired from the CIA due to budget cuts and is forced to work at a grocery store where Steve is the manager, while Roger makes a bargain to win a bet with a coffee shop musician.
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Hayley wants to save the world through investigative journalism so she becomes an intern for a local news reporter. The reporter turns out to be Roger, who gets ratings through sensationalized stories.
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Hayley is injured in a fire and while she is in the hospital she meets Millionaire Matt Davis. As Hayley and Matt fall in love, Steve discovers Jeff Fischer is still alive in outer space.
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Greg and Terry adopt a ten-year-old boy named Michael. At a party celebrating the decision, Roger is jealous of Greg and Terry's lifestyle of culture. Roger rejects the Smith family as trashy and impersonates Michael.
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Roger pushes himself to the breaking point by working non-stop at his bar. When he suffers a heart attack, Roger decides to sell the bar to a company that promises to continue his vision but the bar has been remade as a family restaurant.
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Roger has been acting needy with the family. He senses something in the air that is affecting his behavior but he can't tell where its coming from. Roger leads Francine to a forest where they find a crashed ship, with the alien still alive.
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When Stan doesn't feel confident in anything but his suits, Roger assumes a fashion designer persona to craft him a life-changing new wardrobe. Hayley and Jeff raise chickens in the back yard.
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